Redoxing calcium from the ER.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 15652474.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Inositol 1,4,5-trisphosphate (InsP(3))-induced calcium release from the endoplasmic reticulum (ER) intracellular calcium store regulates cellular functions from the beginning of life at fertilization until death. In this issue of Cell, Mikoshiba and colleagues describe a novel mode of regulation of the InsP(3) receptor (InsP(3)R) governed by ER luminal redox status, calcium, and pH .
Medical subject headings
- Calcium
- Calcium Channels
- Endoplasmic Reticulum
- Inositol 1,4,5-Trisphosphate
- Receptors, Cytoplasmic and Nuclear