Letrozole significantly improves growth potential in a pubertal boy with growth hormone deficiency.
case_report · Level V
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- Record sourced from PubMed, PMID 15653791.
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Abstract
Clinical experience with using an aromatase inhibitor to suppress estrogen production during puberty for improvement of growth potential in adolescents with short stature is limited. This report documents treatment of such a patient with a combination of growth hormone and letrozole, a third-generation aromatase inhibitor. Our case demonstrates a favorable outcome on a short-term basis.
Medical subject headings
- Aromatase Inhibitors
- Growth Disorders
- Human Growth Hormone
- Nitriles
- Triazoles