Resistance to dual nucleoside reverse-transcriptase inhibitors in children infected with HIV clade A/E.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 15655753.
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Abstract
The prevalence of nucleoside reverse-transcriptase inhibitor (NRTI) mutations was determined among 95 human immunodeficiency virus-infected Thai children who were treated with dual nucleoside reverse-transcriptase inhibitors. Almost all children had resistance to at least 1 NRTI, and approximately half of the children had resistance to multiple NRTIs. Cross-resistance to stavudine and azidothymidine was universal.
Medical subject headings
- Drug Resistance, Multiple, Viral
- HIV Infections
- HIV-1
- Reverse Transcriptase Inhibitors