Differentiation of human embryonic stem cells occurs through symmetric cell division.

Zwaka, Thomas P; Thomson, James A · Stem Cells · 2005

basic_science · Level V

Where this comes from

Abstract

Embryonic (ES) stem cells can be expanded indefinitely, yet retain the ability to form all cell types of the body. Here we report that human ES cells differentiate exclusively by symmetric cell division in each of four distinct differentiation conditions examined. This suggests that, in some respects, ES cells more closely resemble precursor or transit amplifying cells rather than adult stem cells.

Medical subject headings