The spanish connection: transcription and mRNA processing get even closer.

Ares, Manuel; Proudfoot, Nick J · Cell · 2005

review · Level V

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Abstract

The synthesis of mRNA by RNA polymerase II appears coupled to numerous RNA-processing events, based on physical or functional connections revealed by biochemical or genetic tests. New findings were presented at a recent meeting in Spain that begin to illuminate the mechanisms underlying the connections between mRNA processing and specific steps in transcription (initiation, elongation, and termination) as well as recombination.

Medical subject headings