Use of ultrasound contrast agents for gene or drug delivery in cardiovascular medicine.
review · Level V
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- Record sourced from PubMed, PMID 15680708.
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Abstract
The clinical utility of ultrasound contrast agents has been established in diagnostic echocardiography. Recently, the use of such agents has been promoted for transport and delivery of various bioactive substances, thus providing a technique for non-invasive gene therapy and organ-specific drug delivery. In this review, we give a critical update of published studies using ultrasound contrast agents for therapeutic use. We discuss the potential applications and limitations of this technique and suggest future applications in cardiovascular medicine.
Medical subject headings
- Drug Delivery Systems
- Gene Transfer Techniques
- Genetic Therapy
- Microbubbles