First fracture is associated with increased risk of new fractures during growth.

Goulding, Ailsa; Jones, Ianthe E; Williams, Sheila M; Grant, Andrea M; Taylor, Rachael W; Manning, Patrick J; Langley, John · J Pediatr · 2005

retrospective_cohort · Level III

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Abstract

Prior fracture was associated with increased risk of new fracture in 601 members of a cohort studied between birth and l8 years. Hazard ratios for new fracture in data adjusted for age and sex were l.90 (95%CI l.51-2.39) after first fracture and 3.04 (95% CI 2.23-4.15) after second fracture.

Medical subject headings