Scleroderma-like skin indurations in a child with phenylketonuria: a clinicopathologic correlation and review of the literature.

Nova, M P; Kaufman, M; Halperin, A · J Am Acad Dermatol · 1992

case_report · Level V

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Abstract

Scleroderma-like skin lesions are one sequela of phenylketonuria. We describe a child with phenylketonuria and associated dermal connective tissue changes consistent with early inflammatory scleroderma. The severity of the skin lesions apparently waned with dietary restriction of phenylalanine.

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