Homeobox galore: when reproduction goes RHOX and roll.
review · Level V
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- Record sourced from PubMed, PMID 15707884.
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Abstract
Homeobox transcription factors exert essential roles in embryogenesis and are thought to govern regenerative cell differentiation. In this issue of Cell, MacLean and colleagues (MacLean et al., 2005) describe a new homeobox gene cluster composed of genes selectively expressed in reproductive tissues. Remarkably, the cluster is on the X chromosome, and the genes display a colinear pattern of expression.
Medical subject headings
- Gametogenesis
- Genes, Homeobox
- Gonads
- Organogenesis
- Sex Differentiation