Glial control of synaptogenesis.
review · Level V
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Abstract
Though all communication between neurons occurs through synapses, we know surprisingly little about the mechanisms inducing their formation. In this issue of Cell, Barres and colleagues (Christopherson et al., 2005) demonstrate that glial-derived thrombospondins and additional soluble glial-secreted factors regulate synapse assembly and functional maturation.
Medical subject headings
- Central Nervous System
- Growth Cones
- Neuroglia
- Synapses
- Thrombospondins