Treatment of endocarditis due to Pseudomonas aeruginosa with imipenem.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 1571451.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Therapy for endocarditis due to Pseudomonas aeruginosa is complicated by the emergence of resistance during therapy, lack of universally available synergistic antimicrobial agents, and unacceptably high morbidity and mortality rates. The authors report a case of aortic valve endocarditis due to P. aeruginosa in which resistance to piperacillin developed during combined therapy with tobramycin. Bacteriologic cure was obtained with a combination of imipenem/cilastatin and tobramycin. The authors review six other cases of P. aeruginosa endovascular infections treated with imipenem.
Medical subject headings
- Anti-Bacterial Agents
- Cilastatin
- Endocarditis, Bacterial
- Imipenem
- Pseudomonas Infections
- Tobramycin