Clinical and radiological deterioration in a patient with AIDS.
case_report · Level V
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Abstract
Paradoxical clinical deterioration of miliary tuberculosis, characterized by pulmonary and abdominal manifestations, is reported in a patient with the acquired immunodeficiency syndrome, after initiation of treatment with highly active antiretroviral therapy. Paradoxical reaction was attributed to partial restoration of cell-mediated immunity related to highly effective antiretroviral therapy. Because tuberculosis has a high prevalence in HIV patients and tuberculosis is often characterized by miliary spreading of disease in these patients, it is important to recognize this phenomenon.
Medical subject headings
- Acquired Immunodeficiency Syndrome
- Antiretroviral Therapy, Highly Active
- Tuberculosis, Miliary
- Tuberculosis, Pulmonary