Resolution of peanut allergy following bone marrow transplantation for primary immunodeficiency.
case_report · Level V
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- Record sourced from PubMed, PMID 15727591.
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Abstract
Peanut allergy is a severe and life-threatening form of food allergy. Treatments are being developed but the mainstays of current management remain avoidance of peanut and appropriate use of rescue medication. We report the case of a boy with peanut allergy who required a bone marrow transplant (BMT) for combined immunodeficiency. A food challenge, 2 years after transplant, showed that his peanut allergy had resolved. Allergic disorders constitute a form of immune deviation and while we do not advocate BMT as a treatment for peanut allergy, we believe this case provides an insight into the basic mechanisms involved in food allergy.
Medical subject headings
- Bone Marrow Transplantation
- Immunologic Deficiency Syndromes
- Peanut Hypersensitivity