Polymerase chain reaction amplification as a diagnostic tool in culture-negative multiple-valve endocarditis.

Madershahian, Navid; Strauch, Justus T; Breuer, Martin; Bruhin, Raimund; Straube, Eberhard; Wahlers, Thorsten · Ann Thorac Surg · 2005

case_report · Level V

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Abstract

We report a case of culture-negative infectious endocarditis in a 17-year-old boy in which the etiologic diagnosis could only be provided by polymerase chain reaction amplification and sequencing of the bacterial 16S rRNA gene from valve tissue.

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