Detection of t(14;18)(q32;q21) in B-cell chronic lymphocytic leukemia.
case_report · Level V
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Abstract
Cytomorphologic testing and multiparameter flow cytometry are the mainstays in diagnosing B-cell chronic lymphocytic leukemia, whereas fluorescence in situ hybridization that targets the translocation t(14;18)(q32;q21) often is used to identify follicular lymphoma. Therapy is highly diverse between both diseases. We describe a case with cytomorphologically and immunologically proven B-cell chronic lymphocytic leukemia in which t(14;18)(q32;q21) was found.
Medical subject headings
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 18
- Leukemia, Lymphocytic, Chronic, B-Cell
- Translocation, Genetic