Protein structure topological comparison, discovery and matching service.
basic_science · Level V
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- Record sourced from PubMed, PMID 15741246.
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Abstract
We describe a fold level fast protein comparison and motif matching facility based on the TOPS representation of structure. This provides an update to a previous service at the EBI, with a better graph matching with faster results and visualization of both the structures being compared against and the common pattern of each with the target domain. Web service at http://balabio.dcs.gla.ac.uk/tops or via the main TOPS site at http://www.tops.leeds.ac.uk. Software is also available for download from these sites.
Medical subject headings
- Algorithms
- Computer Graphics
- Models, Chemical
- Models, Molecular
- Proteins
- Sequence Alignment
- Sequence Analysis, Protein
- User-Computer Interface