SNP discovery using advanced algorithms and neural networks.
other · Level V
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- Record sourced from PubMed, PMID 15746291.
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Abstract
Forage is an application which uses two neural networks for detecting single nucleotide polymorphisms (SNPs). Potential SNP candidates are identified in multiple alignments. Each candidate is then represented by a vector of features, which is classified as SNP or monomorphic by the networks. A validated dataset of SNPs was constructed from experimentally verified SNP data and used for network training and method evalutation. The package is available at biobase.biotech.kth.se/forage/
Medical subject headings
- Algorithms
- Chromosome Mapping
- DNA Mutational Analysis
- Neural Networks, Computer
- Polymorphism, Single Nucleotide
- Sequence Alignment
- Sequence Analysis, DNA