Aspirin use during early pregnancy and the risk of congenital abnormalities: a population-based case-control study.

Nørgård, Bente; Puhó, Erzsébet; Czeizel, Andrew E; Skriver, Mette V; Sørensen, Henrik T · Am J Obstet Gynecol · 2005

case_control · Level III

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Abstract

It is still controversial whether aspirin use during pregnancy increases the risk of certain congenital abnormalities (in particular, neural tube defects, gastroschisis, and cleft lip +/- palate). We examined the risk of selected congenital abnormalities in a large case-control dataset from Hungary and found no increased risk of such congenital abnormalities.

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