CSF cholecystokinin concentrations in patients with panic disorder and in normal comparison subjects.
case_control · Level III
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- Record sourced from PubMed, PMID 1575262.
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Abstract
Cholecystokinin concentrations in the CSF of 25 patients with panic disorder and 16 normal comparison subjects were ascertained by radioimmunoassay. The patients with panic disorder had significantly lower CSF concentrations of cholecystokinin, which may reflect increased CNS cholecystokinin receptor sensitivity, reduced numbers of receptors, or a compensatory reduction in cholecystokinin octapeptide secondary to theoretically increased central cholecystokinin tetrapeptide activity.
Medical subject headings
- Cholecystokinin
- Panic Disorder