Learning from failure: congestive heart failure in the postgenomic age.
review · Level V
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- Record sourced from PubMed, PMID 15765130.
- Also identified by PMC identifier 1052014.
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Abstract
The prognosis of heart failure is worse than that of most cancers, but new therapeutic interventions using stem and other cell-based therapies are succeeding in the fight against it, and old drugs, with new twists, are making a comeback. Genetically engineered animal models are driving insights into the molecular mechanisms that cause hearts to fail, accelerating drug discoveries, and inspiring cell-based therapeutic interventions for both acquired and inheritable cardiac diseases.
Medical subject headings
- Genomics
- Heart Failure