Mitochondrial energy metabolism in heart failure: a question of balance.
review · Level V
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- Record sourced from PubMed, PMID 15765136.
- Also identified by PMC identifier 1052011.
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Abstract
The mitochondrion serves a critical role as a platform for energy transduction, signaling, and cell death pathways relevant to common diseases of the myocardium such as heart failure. This review focuses on the molecular regulatory events and downstream effector pathways involved in mitochondrial energy metabolic derangements known to occur during the development of heart failure.
Medical subject headings
- Cardiac Output, Low
- Energy Metabolism
- Mitochondria
- Myocardium