Death begets failure in the heart.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 15765138.
- Also identified by PMC identifier 1052022.
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Abstract
Recently, low--but abnormal--rates of cardiomyocyte apoptosis have been observed in failing human hearts. Genetic and pharmacological studies suggest that this cell death is causally linked to heart failure in rodent models. Herein, we review these data and discuss potential therapeutic implications.
Medical subject headings
- Apoptosis
- Cardiac Output, Low
- Myocytes, Cardiac