Xanthoma disseminatum with bilateral epibulbar involvement.

Abstract

To describe the ocular involvement in xanthoma disseminatum. Case report and literature review. Histopathologic study of excised conjunctival tumor and clinical follow-up. A 29-year-old woman with normal serum lipoproteins developed widespread xanthomas of the skin, throat, and episclera. There were no signs of recurrence 12 months after removal of the conjunctival xanthomas. Xanthoma disseminatum is a rare condition for which there is no medical treatment. The distinction between the normolipemic xanthomatoses awaits a better understanding of their pathogenesis. Surgical removal of episcleral xanthomas can be successful, but long-term follow-up of such patients has been limited.