The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease.

Maschke, M; Tuite, P J; Pickett, K; Wächter, T; Konczak, J · J Neurol Neurosurg Psychiatry · 2005

case_control · Level III

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Abstract

Parkinson's disease is accompanied by deficits in passive motion and limb position sense. To investigate whether deep brain stimulation of the subthalamic nucleus (STN-DBS) reverses these proprioceptive deficits. A passive movement task was applied to nine patients with Parkinson's disease and bilateral chronic STN-DBS and to seven controls. Thresholds for 75% correct responses were 0.9 degrees for controls, 2.5 degrees for Parkinson's disease patients when stimulation was OFF, and 2.0 degrees when stimulation was ON. STN-DBS improves kinaesthesic deficits in Parkinson's disease, but does not lead to a full recovery of proprioceptive function.

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