Management of early viable cervical pregnancy.

Mesogitis, Spiros; Pilalis, Athanasios; Daskalakis, George; Papantoniou, Nikolaos; Antsaklis, Aris · BJOG · 2005

prospective_cohort · Level II

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Abstract

To evaluate conservative management of early viable cervical pregnancy. Prospective study. A tertiary teaching hospital. All cases of cervical pregnancies with fetal cardiac activity presenting to our hospital over six years. All cases were managed with trans-abdominal intra-amniotic injection of 25 mg of methotrexate under ultrasound guidance. Follow up sonographic examinations and serum beta-hCG measurements were performed every three days. Cervical curettage was performed after two follow up ultrasound examinations had shown a dead fetus and a regressing gestational sac as well as declining beta-hCG levels. Patients were managed as outpatients. Successful management and need for hospitalisation. Nine cases were encountered. Two required a second injection of methotrexate for persistent fetal cardiac activity and serum beta-hCG rise in the follow up examination. We did not observe any side effects and no patient required admission to the hospital. Intra-amniotic methotrexate injection and subsequent cervical curettage after one week is a successful alternative for the management of cervical pregnancies.

Medical subject headings