Cardiotoxic effects of astemizole overdose in children.
case_report · Level V
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- Record sourced from PubMed, PMID 1578320.
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Abstract
Astemizole, a nonsedating antihistamine, caused a prolonged corrected QT interval, ventricular dysrhythmias, and atrioventricular heart block after overdose in five children. Cardiotoxic effects lasted an average of 2 1/2 days. Children poisoned with astemizole need emergent medical evaluation, a 12-lead electrocardiogram with calculation of the corrected QT interval, and continuous cardiac monitoring for 24 hours.
Medical subject headings
- Arrhythmias, Cardiac
- Astemizole
- Heart Block