Statins--a cure-all for the brain?
review · Level V
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- Record sourced from PubMed, PMID 15803163.
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Abstract
'Statins' are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors - oral cholesterol-lowering drugs that are used to treat hypercholesterolaemia. It is widely accepted that statins have anti-inflammatory effects that are independent of their ability to lower cholesterol. Animal studies and observational clinical studies have indicated that statins might also be effective in treating certain neurological diseases - in particular, multiple sclerosis, Alzheimer's disease and ischaemic stroke. At present, however, results from ongoing prospective, randomized clinical trials are not available.
Medical subject headings
- Brain
- Central Nervous System Diseases
- Hydroxymethylglutaryl-CoA Reductase Inhibitors