Genetics and the variability of treatment response in asthma.
review · Level V
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- Record sourced from PubMed, PMID 15806036.
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Abstract
Pharmacogenetics is the study of how genetic differences influence the variability in patients' responses to therapy. Using specific examples in asthma, I will define the concepts of variability in response to therapy in asthma. I will then use the relationship between specific genetic polymorphisms and the response to beta-adrenergic agonists and leukotriene modifiers to illustrate pharmacogenetic interactions and to acquaint the reader with the applicability of these findings to clinical practice.
Medical subject headings
- Anti-Asthmatic Agents
- Asthma
- Pharmacogenetics