pFind: a novel database-searching software system for automated peptide and protein identification via tandem mass spectrometry.
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Abstract
Research in proteomics requires powerful database-searching software to automatically identify protein sequences in a complex protein mixture via tandem mass spectrometry. In this paper, we describe a novel database-searching software system called pFind (peptide/protein Finder), which employs an effective peptide-scoring algorithm that we reported earlier. The pFind server is implemented with the C++ STL, .Net and XML technologies. As a result, high speed and good usability of the software are achieved.
Medical subject headings
- Database Management Systems
- Databases, Protein
- Mass Spectrometry
- Proteins
- Sequence Alignment
- Sequence Analysis, Protein
- Software