Melanocyte stem cell maintenance and hair graying.
review · Level V
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Abstract
Hair graying is an obvious sign of human aging, yet little was known about its causes. Two recent papers provide compelling evidence that hair graying is due to incomplete melanocyte stem cell maintenance and identify Pax3 and Mitf as key molecules that help regulate the balance between melanocyte stem cell maintenance and differentiation.
Medical subject headings
- Aging
- Hair Color
- Hair Follicle
- Melanocytes
- Multipotent Stem Cells