Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis.
retrospective_cohort · Level III
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Abstract
In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus-uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21-139 days) and persisting for a median of 67.5 days (interquartile range, 34-111 days). We found no association between the use of steroids and the duration of reaction.
Medical subject headings
- Adrenal Cortex Hormones
- Antitubercular Agents
- Tuberculosis, Lymph Node