Programmable DNA self-assemblies for nanoscale organization of ligands and proteins.
basic_science · Level V
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Abstract
We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimensional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.
Medical subject headings
- DNA
- Nanostructures
- Nanotechnology
- Proteins