The many faces of sequence alignment.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 15826353.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Starting with the sequencing of the mouse genome in 2002, we have entered a period where the main focus of genomics will be to compare multiple genomes in order to learn about human biology and evolution at the DNA level. Alignment methods are the main computational component of this endeavour. This short review aims to summarise the current status of research in alignments, emphasising large-scale genomic comparisons and suggesting possible directions that will be explored in the near future.
Medical subject headings
- Algorithms
- Models, Genetic
- Pattern Recognition, Automated
- Sequence Alignment
- Sequence Analysis, DNA
- Sequence Analysis, Protein