Escherichia coli: development of carbapenem resistance during therapy.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 15844056.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A 76-year-old woman had recurrent urosepsis due to extended-spectrum beta -lactamase-positive Escherichia coli. Imipenem resistance was detected after long-term imipenem-meropenem therapy. The carbapenem-hydrolyzing enzyme gene was identified as blaKPC-3. To our knowledge, this is the first documented case in which carbapenem-resistant E. coli emerged during therapy with imipenem and meropenem, and the first identification of the carbapenem-hydrolyzing enzyme in E. coli isolates.
Medical subject headings
- Drug Resistance, Bacterial
- Escherichia coli
- Escherichia coli Infections
- Imipenem