Association mapping and fine mapping with TreeLD.
other · Level V
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- Record sourced from PubMed, PMID 15855250.
- Also identified by PMC identifier 2587010.
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Abstract
The program package TreeLD implements a unified approach to association mapping and fine mapping of complex trait loci and a novel approach to visualizing association data, based on an inferred ancestry of the sample. Fundamentally, the TreeLD approach is based on the idea that the evidence for association at a particular position is contained in the ancestral tree relating the sampled chromosomes at that position. TreeLD provides an easy-to-use interface and can be applied to case-control, TDT trio and quantitative trait data.
Medical subject headings
- Algorithms
- Chromosome Mapping
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Software
- User-Computer Interface