Combination treatment strategies in early rheumatoid arthritis.

Suresh, E; Lambert, C M · Ann Rheum Dis · 2005

review · Level V

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Abstract

Combinations of disease modifying antirheumatic drugs (DMARDs) are increasingly being used in patients with early rheumatoid arthritis (RA) when long term results with sequential DMARD monotherapy are disappointing. Combination DMARD therapy may be more effective than monotherapy, and has no additional short term adverse events. The evidence for using combination DMARD therapy is still weak, however, and further trials are needed.

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