Uterine sarcoidosis potentially associated with interferon-alpha use for chronic hepatitis C infection.

Tsiodras, Sotirios; Drimala, Panagiota; Stavreas, Nick; Dachlythras, Marios; Alamani, Anna Maria; Naoum, George · Obstet Gynecol · 2005

case_report · Level V

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Abstract

A regimen including interferon-alpha has become the standard of care in the treatment of chronic hepatitis C over the last decade. One rare adverse effect associated with the use of interferon-alpha is a granulomatous pulmonary reaction. A unique case of uterine sarcoidosis associated with the use of interferon-alpha for chronic hepatitis C infection is presented. Gynecologists should be aware of a potential association between interferon-alpha therapy and granulomatous reactions occurring not only in the lung but also in the female genital tract.

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