A method and technical equipment for an acute human trial to evaluate retinal implant technology.
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Abstract
This paper reports on methods and technical equipment to investigate the epiretinal stimulation of the retina in blind human subjects in acute trials. Current is applied to the retina through a thin, flexible microcontact film (microelectrode array) with electrode diameters ranging from 50 to 360 microm. The film is mounted in a custom-designed surgical tool that is hand-held by the surgeon during stimulation. The eventual goal of the work is the development of a chronically implantable retinal prosthesis to restore a useful level of vision to patients who are blind with outer retinal degenerations, specifically retinitis pigmentosa and macular degeneration.
Medical subject headings
- Blindness
- Clinical Trials as Topic
- Electric Stimulation Therapy
- Electrodes, Implanted
- Equipment Failure Analysis
- Microelectrodes
- Prostheses and Implants
- Retina