Phase II study of radiochemotherapy with vinblastine in invasive bladder cancer.

Kragelj, Borut; Zaletel-Kragelj, Lijana; Sedmak, Boris; Cufer, Tanja; Cervek, Jozica · Radiother Oncol · 2005

prospective_cohort · Level II

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Abstract

Concurrent vinablastine-based radiochemotherapy was evaluated in 84 bladder-cancer patients. It was effective in more than half: tumour-specific survival (51% 9-year), local control rate (55% 9-year). The drawback was the impaired function of the bladder (9-year prevalence SOMA G3-4 symptoms: 66%), indicating the need for treatment aimed at reducing chronic morbidity.

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