SDMinP: a program to control the family wise error rate using step-down minP adjusted P-values.

Obreiter, M; Fischer, C; Chang-Claude, J; Beckmann, L · Bioinformatics · 2005

other · Level V

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Abstract

SDMinP is an easy-to-use program for fast calculation of empirical and adjusted P-values for correlated and uncorrelated hypotheses in multiple testing experiments. It is based on the Free Step-Down Resampling Method for controlling the family wise error rate, and implements a variation of an efficient algorithm, which reduces the originally required re-sampling effort considerably and makes the method computationally feasible. The program is independent of the underlying test statistic and works with provided observed and permutation test statistics.

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