Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma.
review · Level V
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Abstract
Substantial effort has focused on the development of novel targeted agents for treating patients with late-stage colorectal carcinoma. These agents are designed specifically to inhibit biochemical processes associated with pathogenesis. Numerous molecules targeting the epidermal growth factor receptor have been investigated as therapeutic agents and appear to herald a shift in the treatment paradigm for colorectal carcinoma.
Medical subject headings
- Antibodies, Monoclonal
- Antineoplastic Agents
- Colorectal Neoplasms
- ErbB Receptors