Cre-ating somatic cell genetic mosaics in the mouse.
basic_science · Level V
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Abstract
Generation of somatic mosaics in which mutant cell clones are uniquely and completely labeled has yielded considerable insight into many biological processes in Drosophila. In this issue of Cell, describe a novel method called MADM that allows the generation of such mosaics in mice.
Medical subject headings
- Integrases
- Mosaicism
- Recombination, Genetic