The use of oscillatory signals in the study of genetic networks.

Lipan, Ovidiu; Wong, Wing H · Proc Natl Acad Sci U S A · 2005

other · Level V

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Abstract

The structure of a genetic network is uncovered by studying its response to external stimuli (input signals). We present a theory of propagation of an input signal through a linear stochastic genetic network. We found that there are important advantages in using oscillatory signals over step or impulse signals and that the system may enter into a pure fluctuation resonance for a specific input frequency.

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