SCHIP: statistics for chromosome interphase positioning based on interchange data.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 15886279.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The position of chromosomes in the interphase nucleus is believed to be associated with a number of biological processes. Here, we present a web-based application that helps analyze the relative position of chromosomes during interphase in human cells, based on observed radiogenic chromosome aberrations. The inputs of the program are a table of yields of pairwise chromosome interchanges and a proposed chromosome geometric cluster. Each can either be uploaded or selected from provided datasets. The main outputs are P-values for the proposed chromosome clusters. SCHIP is designed to be used by a number of scientific communities interested in nuclear architecture, including cancer and cell biologists, radiation biologists and mathematical/computational biologists.
Medical subject headings
- Chromosome Aberrations
- Chromosome Mapping
- Interphase
- Models, Genetic
- Sister Chromatid Exchange
- Software
- User-Computer Interface