Systemic pyoderma gangrenosum responding to infliximab and adalimumab.
case_report · Level V
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- Record sourced from PubMed, PMID 15888172.
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Abstract
Pyoderma gangrenosum (PG) is frequently associated with constitutional symptoms as part of a nonspecific inflammatory response. However, extracutaneous discrete aseptic neutrophilic infiltrates are extremely rare. We report a patient with idiopathic PG with splenic and psoas muscle involvement. His disease was extremely aggressive and was unresponsive to conventional immunosuppressive therapy. His cutaneous and extracutaneous PG cleared with infliximab and adalimumab.
Medical subject headings
- Antibodies, Monoclonal
- Dermatologic Agents
- Pyoderma Gangrenosum