Factors affecting the long-term patency of crossover femorofemoral bypass graft.

Abstract

To determine the factors affecting long-term patency of crossover femorofemoral bypass (FFB) graft. A retrospective clinical study of a prospectively registered database. Two hundred and sixteen FFBs performed for 192 patients with atherosclerotic iliac occlusive disease. The clinical and surgical variables influencing graft patency were assessed with log-rank test and Cox's proportional hazard analysis. The primary patency rates of all FFB grafts at 3 and 5 years were 73+/-4 and 65+/-5%, respectively. By multivariate analysis, hypertension (Odds ratio 2.8, P=0.002) and critical ischemia (Odds ratio 0.42, P=0.01) significantly (P<.05) influenced long-term patency of FFB grafts. The long-term patency of FFB grafts was not affected by procedural modifications. Graft patency was inferior in patients with severe lower limb ischemia but superior in patients with hypertension. Further study is required to clarify the mechanism of an unexpected beneficial effect of hypertension on FFB graft patency.