Testotoxicosis: gonadotrophin-independent male sexual precocity.
case_report · Level V
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- Record sourced from PubMed, PMID 1589386.
- Also identified by PMC identifier 2399261.
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Abstract
In this era of rapidly developing investigational tools and pharmacology, the pathophysiology of precocious puberty is becoming well defined. What was previously thought to be a form of gonadotrophin releasing hormone (GNRH)-dependent central precocious puberty is now classified as GNRH-independent familial testotoxicosis. We present two such cases and review the clinical features, pathophysiology and treatment of testotoxicosis.
Medical subject headings
- Puberty, Precocious
- Testosterone