Temporal regulation of planar cell polarity: insights from the Drosophila eye.

Schweisguth, François · Cell · 2005

basic_science · Level V

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Abstract

In this issue of Cell, identify a first regulatory link between planar cell polarity (PCP) signaling and apical-basal polarity. The authors propose that a component of the apical Crumbs complex regulates the phosphorylation of the Frizzled (Fz) PCP receptor, thus modulating PCP in the Drosophila eye.

Medical subject headings