Successful treatment with miltefosine of disseminated cutaneous leishmaniasis in a severely immunocompromised patient infected with HIV-1.
case_report · Level V
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Abstract
We describe here a case of disseminated cutaneous leishmaniasis due to Leishmania major in a severely immunocompromised patient from Burkino Faso, Africa, who is infected with human immunodeficiency virus-1. The skin lesions failed to respond to full treatment courses of amphotericin B, sodium stibogluconate, and liposomal amphotericin B but were successfully treated with miltefosine, an alkylphosphocholine analogue.
Medical subject headings
- Antiprotozoal Agents
- HIV Infections
- Immunocompromised Host
- Leishmaniasis, Diffuse Cutaneous
- Phosphorylcholine