Efficient recognition of folds in protein 3D structures by the improved PRIDE algorithm.
basic_science · Level V
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Abstract
An improved version of the PRIDE (PRobaility of IDEntity) fold prediction algorithm has been developed, based on more solid statistical basis, fast search capabilities and efficient input structure processing. The new algorithm is effective in identifying protein structures at the 'H' level of the CATH hierarchy. The new algorithm is integrated into the PRIDE2 web servers at http://pride.szbk.u-szeged.hu and http://www.icgeb.org/pride. Detailed documentation and performance evaluation is available in the description section of the PRIDE2 web server.
Medical subject headings
- Algorithms
- Models, Chemical
- Models, Molecular
- Proteins
- Sequence Analysis, Protein
- Software
- User-Computer Interface